Excipients: The Real Players behind Robust Formulation
نویسندگان
چکیده
منابع مشابه
Formulation and evaluation of lansoprazole orodispersable tablets using novel excipients
In the present work an attempt has been made to increase the solubility and dissolution rate of lansprozole by formulating it as solid dispersions by lipid carriers such as compritol 888 ATO Phospholipon 90 H and Lipoid S100 by using Fusion method, Kneading method and solvent evaporation method. Further the solid dispersions were compressed as orodispersible tablets by using croscarmelloe sodiu...
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Strict measure on the need to control microbial contamination in the formulation of solid dosage forms such as tablets and capsules are not usually in place as is done in other pharmaceutical preparations. The presence of microorganisms in some common excipients such as starch and lactose powders, and distilled water used in tablet formulation was investigated in this study. Organisms isolated ...
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A variety of excipients are used to stabilize proteins, suppress protein aggregation, reduce surface adsorption, or to simply provide physiological osmolality. The stabilizers encompass a wide variety of molecules including sugars, salts, polymers, surfactants, and amino acids, in particular arginine. The effects of these excipients on protein stability in solution are mainly caused by their in...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Education and Research
سال: 2019
ISSN: 0019-5464
DOI: 10.5530/ijper.53.1.2